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Celexa - [ Citalopram Hydrobromide ] - Celexa is the brand name used for Citalopram HBr by Forest Pharmaceuticals. Citalopram is an oral medication used for the treatment of drepression.
Citalopram is not a monoamine oxidase inhibitor (MAOI: the most common form of antidepressant). Instead, Citalopram is an antidepressant that is a member of the family of drugs known as selective serotonin reuptake inhibitors (SSRIs). Citalopram helps to restore the brain's chemical balance by increasing the supply of a substance in the brain called serotonin. Citalopram appears to relieve depression by increasing serotonin without affecting many of the other chemicals in the brain that influence mood.

HOW SSRIs WORK: Although the brain chemistry of depression is not fully understood, there does exist a growing body of evidence to support the view that people with depression have an imbalance of the brain’s neurotransmitters. These are chemicals in the brain that allow nerve cells to communicate. One of these neurotransmitters is serotonin. An imbalance in serotonin may be an important factor in the development and severity of depression. SSRIs affect how much serotonin is available by blocking its reabsorption during transmission from one nerve cell in the brain to another. Serotonin is released from one nerve cell and passed to the next. In the process, some of the serotonin released is reabsorbed by the first nerve cell. SSRIs block the reabsorption of serotonin into the first nerve cell. It is this blocking action that causes an increased amount of serotonin to become available at the next nerve cell. This is how SSRIs affect the balance of serotonin in the brain.

WHEN YOU SHOULD NOT USE THIS MEDICINE: You should not use this medicine if you have had an allergic reaction to citalopram. You should not use citalopram within 14 days before or after taking an MAO (monoamine oxidase) inhibitor such as phenelzine (Nardil ®), isocarboxazid (Marplan ®), tranylcypromine (Parnate ®), or selegeline (Eldepryl ®).

Ephedrine - [ Ephedrine Hydrochloride ] - Ephedrine, also called Ma Huang, Ephedra, epitonin, and/or Chinese ephedra, is found in numerous diet supplements, muscle enhancers, appetite suppressants from makers such as Metabolife, Advocare, Metabolite, and Metab-Rx Ultra.
Pseudo-ephedrine hydrocloride is used as over the counter nasal decongestant medicine, in such products as Suphedrine, NyQuil, et al.

Ephedrine HCl is a sympathomimetic drug that relaxes smooth muscle and constricts blood vessels. It was formerly widely used as a bronchodilator in the treatment of such conditions as asthma and chronic bronchitis, but has largely been replaced for treating these conditions by drugs that have fewer adverse effects. Its main use now is as a nasal decongestant (alone or in combination with other drugs) and it is included as an ingredient in many medicines for treating colds and coughs. It is also used to treat bedwetting in children. Ephedrine hydrochloride is available as tablets or an injection on prescription only and as an elixir or nose drops that can be bought from pharmacies without a prescription.

The central stimulant effects of Ephedrine are more marked than those of epinephrine. In general, the effects of ephedrine are similar to those observed with epinephrine but are slower in onset, less potent, and longer in duration. However, in the uterus, Ephedrine produces dilatation of uterine muscle; Ephedrine is also less effective than epinephrine in elevating the blood sugar concentration.




Links: - Forest Pharmaceuticals, Inc. public relations site - contains details on Ephedrine